Natively Unfolded FG Repeats Stabilize the Structure of the Nuclear Pore Complex

Natively Unfolded FG Repeats Stabilize the Structure of the Nuclear Pore Complex

Nuclear pore complexes (NPCs) are ∼100 MDa transport channels assembled from multiple copies of ∼30 nucleoporins (Nups). One-third of these Nups contain phenylalanine-glycine (FG)-rich repeats, forming a diffusion barrier, which is selectively permeable for nuclear transport receptors that interact...

Full description

Bibliographic Details
Main Authors: Onischenko, Evgeny, Tang, Jeffrey H., Vallotton, Pascal, Derrer, Carina P., Kralt, Annemarie, Mugler, Christopher F., Chan, Leon Y., Weis, Karsten, Andersen, Kasper R., Knockenhauer, Kevin Edward, Schwartz, Thomas
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Elsevier BV 2018
Online Access:http://hdl.handle.net/1721.1/118975
https://orcid.org/0000-0003-2265-5174
https://orcid.org/0000-0001-8012-1512

Internet

http://hdl.handle.net/1721.1/118975
https://orcid.org/0000-0003-2265-5174
https://orcid.org/0000-0001-8012-1512

Similar Items