Resource Competition Shapes the Response of Genetic Circuits

A common approach to design genetic circuits is to compose gene expression cassettes together. While appealing, this modular approach is challenged by the fact that expression of each gene depends on the availability of transcriptional/translational resources, which is in turn determined by the pres...

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Bibliographic Details
Main Authors: Qian, Yili, Huang, Hsin-Ho, Jimenez Zarco, Jose I., Del Vecchio, Domitilla
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Published: American Chemical Society (ACS) 2018
Online Access:http://hdl.handle.net/1721.1/119015
https://orcid.org/0000-0002-1097-0401
https://orcid.org/0000-0003-2435-480X
https://orcid.org/0000-0001-6472-8576