Nicotine promotes neuron survival and partially protects from Parkinson’s disease by suppressing SIRT6
Parkinson’s disease is characterized by progressive death of dopaminergic neurons, leading to motor and cognitive dysfunction. Epidemiological studies consistently show that the use of tobacco reduces the risk of Parkinson’s. We report that nicotine reduces the abundance of SIRT6 in neuronal culture...
Main Authors: | , , , , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
BioMed Central
2018
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Online Access: | http://hdl.handle.net/1721.1/119020 https://orcid.org/0000-0001-8200-6665 |