Analyzing and Exploiting the Effects of Protease Sharing in Genetic Circuits

Degradation of proteins in cells plays a large role in the dynamics of gene networks. This degradation is enabled by proteases, which are found in limited quantities in the cell. Proteins that compete for protease may therefore become coupled by non-explicit interactions, which are often neglected i...

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Bibliographic Details
Main Authors: McBride, Cameron David, Del Vecchio, Domitilla
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Published: Elsevier 2018
Online Access:http://hdl.handle.net/1721.1/119166
https://orcid.org/0000-0002-9163-8821
https://orcid.org/0000-0001-6472-8576