Synthetic Tunable Amplifying Buffer Circuit in E. coli

While predictable design of a genetic circuit's output is a major goal of synthetic biology, it remains a significant challenge because DNA binding sites in the cell affect the concentration of available transcription factors (TF). To mitigate this problem, we propose to use a TF that results f...

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Bibliographic Details
Main Authors: Nilgiriwala, Kayzad, Jimenez Zarco, Jose I., Rivera-Ortiz, Phillip Michael, Del Vecchio, Domitilla
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Published: American Chemical Society (ACS) 2018
Online Access:http://hdl.handle.net/1721.1/119168
https://orcid.org/0000-0001-6472-8576