Linking single-cell measurements of mass, growth rate, and gene expression

Mass and growth rate are highly integrative measures of cell physiology not discernable via genomic measurements. Here, we introduce a microfluidic platform enabling direct measurement of single-cell mass and growth rate upstream of highly multiplexed single-cell profiling such as single-cell RNA se...

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Bibliographic Details
Main Authors: Pelton, Kristine, De Smet, Frederik, Ligon, Keith L., Kimmerling, Robert John, Prakadan, Sanjay, Gupta, Alejandro J., Calistri, Nicholas L, Stevens, Mark M., Olcum, Selim A., Cermak, Nathan, Drake, Riley, Shalek, Alexander K, Manalis, Scott R
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: BioMed Central 2018
Online Access:http://hdl.handle.net/1721.1/119409
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