Layered dynamic regulation for improving metabolic pathway productivity in Escherichia coli

Microbial production of value-added chemicals from biomass is a sustainable alternative to chemical synthesis. To improve product titer, yield, and selectivity, the pathways engineered into microbes must be optimized. One strategy for optimization is dynamic pathway regulation, which modulates expre...

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Bibliographic Details
Main Authors: Doong, Stephanie, Gupta, Apoorv, Jones, Kristala L.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Proceedings of the National Academy of Sciences 2018
Online Access:http://hdl.handle.net/1721.1/119416
https://orcid.org/0000-0001-8089-2034
https://orcid.org/0000-0002-6548-9420
https://orcid.org/0000-0003-0437-3157