MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis

MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis

Chronic inflammation is a major risk factor for colorectal cancer. The p38/MAPKAP Kinase 2 (MK2) kinase axis controls the synthesis of proinflammatory cytokines that mediate both chronic inflammation and tumor progression. Blockade of this pathway has been previously reported to suppress inflammatio...

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Bibliographic Details
Main Authors: Haigis, Kevin M., Suarez Lopez, Lucia, Kong, Yi Wen, Sriram, Ganapathy, Morandell, Sandra M., Merrick, Karl Andrew, Hernandez, Yuliana I, Yaffe, Michael B
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Proceedings of the National Academy of Sciences 2018
Online Access:http://hdl.handle.net/1721.1/119429
https://orcid.org/0000-0002-3719-0536
https://orcid.org/0000-0002-4223-971X
https://orcid.org/0000-0002-1651-3607
https://orcid.org/0000-0003-4082-0292
https://orcid.org/0000-0002-9547-3251

Internet

http://hdl.handle.net/1721.1/119429
https://orcid.org/0000-0002-3719-0536
https://orcid.org/0000-0002-4223-971X
https://orcid.org/0000-0002-1651-3607
https://orcid.org/0000-0003-4082-0292
https://orcid.org/0000-0002-9547-3251

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