MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis
Chronic inflammation is a major risk factor for colorectal cancer. The p38/MAPKAP Kinase 2 (MK2) kinase axis controls the synthesis of proinflammatory cytokines that mediate both chronic inflammation and tumor progression. Blockade of this pathway has been previously reported to suppress inflammatio...
| Main Authors: | , , , , , , , |
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| Format: | Article |
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Proceedings of the National Academy of Sciences
2018
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| Online Access: | http://hdl.handle.net/1721.1/119429 https://orcid.org/0000-0002-3719-0536 https://orcid.org/0000-0002-4223-971X https://orcid.org/0000-0002-1651-3607 https://orcid.org/0000-0003-4082-0292 https://orcid.org/0000-0002-9547-3251 |