Microfluidic models for adoptive cell-mediated cancer immunotherapies

Current adoptive T cell therapies have shown promising results in clinical trials but need further development as an effective cancer treatment. Here, we discuss how 3D microfluidic tumour models mimicking the tumour microenvironment could help in testing T cell immunotherapies by assessing engineer...

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Bibliographic Details
Main Authors: Adriani, Giulia, Pavesi, Andrea, Tan, Anthony T., Bertoletti, Antonio, Thiery, Jean Paul, Kamm, Roger Dale
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Elsevier 2018
Online Access:http://hdl.handle.net/1721.1/119471
https://orcid.org/0000-0002-7232-304X