Mechanistic studies of the anticancer activity of an octahedral hexanuclear Pt(II) cage

Mechanistic studies of the anticancer activity of an octahedral hexanuclear Pt(II) cage

The cellular response evoked by a hexanuclear platinum complex, Pt6L4(1), is reported. Compound 1, a 3-nm octahedral cage formed by self-assembly of six Pt(II) centers and four 2,4,6-tris(4-pyridyl)-1,3,5-triazine ligands (L), exhibits promising in vitro potency against a panel of human cancer cell...

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Bibliographic Details
Main Authors: Zheng, Yaorong, Suntharalingam, Kogularamanan, Bruno, Peter Michael, Lin, Wei, Wang, Weixue, Hemann, Michael, Lippard, Stephen J.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Published: Elsevier 2018
Online Access:http://hdl.handle.net/1721.1/119635
https://orcid.org/0000-0003-3383-0118
https://orcid.org/0000-0002-2693-4982

Internet

http://hdl.handle.net/1721.1/119635
https://orcid.org/0000-0003-3383-0118
https://orcid.org/0000-0002-2693-4982

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