Design of Insulin-Loaded Nanoparticles Enabled by Multistep Control of Nanoprecipitation and Zinc Chelation

Nanoparticle (NP) carriers provide new opportunities for controlled delivery of drugs, and have potential to address challenges such as effective oral delivery of insulin. However, due to the difficulty of efficiently loading insulin and other proteins inside polymeric NPs, their use has been mostly...

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Bibliographic Details
Main Authors: Chopra, Sunandini, Bertrand, Nicolas, Lim, Jong-Min, Wang, Amy, Farokhzad, Omid C, Karnik, Rohit
Other Authors: Institute for Medical Engineering and Science
Format: Article
Published: American Chemical Society (ACS) 2018
Online Access:http://hdl.handle.net/1721.1/119690
https://orcid.org/0000-0003-1856-1925
https://orcid.org/0000-0002-2640-3006
https://orcid.org/0000-0003-0588-9286