Design of Insulin-Loaded Nanoparticles Enabled by Multistep Control of Nanoprecipitation and Zinc Chelation
Nanoparticle (NP) carriers provide new opportunities for controlled delivery of drugs, and have potential to address challenges such as effective oral delivery of insulin. However, due to the difficulty of efficiently loading insulin and other proteins inside polymeric NPs, their use has been mostly...
Main Authors: | Chopra, Sunandini, Bertrand, Nicolas, Lim, Jong-Min, Wang, Amy, Farokhzad, Omid C, Karnik, Rohit |
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Other Authors: | Institute for Medical Engineering and Science |
Format: | Article |
Published: |
American Chemical Society (ACS)
2018
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Online Access: | http://hdl.handle.net/1721.1/119690 https://orcid.org/0000-0003-1856-1925 https://orcid.org/0000-0002-2640-3006 https://orcid.org/0000-0003-0588-9286 |
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