Premature polyadenylation of MAGI3 is associated with diminished N[superscript 6]-methyladenosine in its large internal exon

In cancer, tumor suppressor genes (TSGs) are frequently truncated, causing their encoded products to be non-functional or dominant-negative. We previously showed that premature polyadenylation (pPA) of MAGI3 truncates the gene, switching its functional role from a TSG to a dominant-negative oncogene...

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Bibliographic Details
Main Authors: Ni, Thomas K., Elman, Jessica S., Kuperwasser, Charlotte, Jin, Dexter X., Gupta, Piyush
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/119787
https://orcid.org/0000-0003-1533-6730
https://orcid.org/0000-0002-9703-1780