Microfluidic platform for characterizing TCR–pMHC interactions

The physical characteristics of the T cell receptor (TCR)-peptide-major histocompatibility complex (pMHC) interaction are known to play a central role in determining T cell function in the initial stages of the adaptive immune response. State-of-the-art assays can probe the kinetics of this interact...

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Bibliographic Details
Main Authors: Stockslager, Max Andrew, Hecht, Vivian Chaya, Hu, Kevin, Aranda-Michel, Edgar C., Kimmerling, Robert John, Manalis, Scott R, Shaw, Josephine, Payer, Kristofor Robert
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: AIP Publishing 2019
Online Access:http://hdl.handle.net/1721.1/119858
https://orcid.org/0000-0003-3415-3614
https://orcid.org/0000-0003-4110-1388
https://orcid.org/0000-0001-9939-764X
https://orcid.org/0000-0001-5223-9433