Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery

Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery

Adoptive cell therapy (ACT) with antigen-specific T cells has shown remarkable clinical success; however, approaches to safely and effectively augment T cell function, especially in solid tumors, remain of great interest. Here we describe a strategy to ‘backpack’ large quantities of supporting prote...

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Bibliographic Details
Main Authors: Tang, Li, Zheng, Yiran, Melo, Mariane Bandeira, Mabardi, Llian, Castaño, Ana P, Xie, Yu-Qing, Li, Na, Kudchodkar, Sagar B, Wong, Hing C, Jeng, Emily K, Maus, Marcela V, Irvine, Darrell J
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Nature Publishing Group 2019
Online Access:http://hdl.handle.net/1721.1/120102
https://orcid.org/0000-0002-4244-5978
https://orcid.org/0000-0003-0817-0525

Internet

http://hdl.handle.net/1721.1/120102
https://orcid.org/0000-0002-4244-5978
https://orcid.org/0000-0003-0817-0525

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