High MITF Expression Is Associated with Super-Enhancers and Suppressed by CDK7 Inhibition in Melanoma

High MITF Expression Is Associated with Super-Enhancers and Suppressed by CDK7 Inhibition in Melanoma

Cutaneous melanoma is an aggressive tumor that accounts for most skin cancer deaths. Among the physiological barriers against therapeutic success is a strong survival program driven by genes such as MITF that specify melanocyte identity, a phenomenon known in melanoma biology as lineage dependency....

Full description

Bibliographic Details
Main Authors: Eliades, Philip, Abraham, Brian J., Ji, Zhenyu, Christensen, Camilla L., Kwiatkowski, Nicholas, Kumar, Raj, Njauw, Ching Ni, Taylor, Michael, Miao, Benchun, Zhang, Tinghu, Wong, Kwok-Kin, Gray, Nathanael S., Tsao, Hensin, Young, Richard A., Miller, David M., III
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Elsevier BV 2019
Online Access:http://hdl.handle.net/1721.1/120115
https://orcid.org/0000-0001-8855-8647

Internet

http://hdl.handle.net/1721.1/120115
https://orcid.org/0000-0001-8855-8647

Similar Items