SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway

SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway

mTOR complex 1 (mTORC1) regulates cell growth and metabolism in response to multiple environmental cues. Nutrients signal via the Rag guanosine triphosphatases (GTPases) to promote the localization of mTORC1 to the lysosomal surface, its site of activation. We identified SAMTOR, a previously unchara...

Full description

Bibliographic Details
Main Authors: Harper, J. Wade, Gygi, Steven P., Gu, Xin, Orozco Segrera, Jose, Saxton, Robert Andrew, Condon, Kendall Janine, Liu, Grace Yun, Krawczyk, Patrycja A., Scaria, Sonia M., Sabatini, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: American Association for the Advancement of Science (AAAS) 2019
Online Access:http://hdl.handle.net/1721.1/120131
https://orcid.org/0000-0002-3393-6927
https://orcid.org/0000-0002-4364-5912
https://orcid.org/0000-0002-9376-3984
https://orcid.org/0000-0002-9515-8892
https://orcid.org/0000-0002-1446-7256

Internet

http://hdl.handle.net/1721.1/120131
https://orcid.org/0000-0002-3393-6927
https://orcid.org/0000-0002-4364-5912
https://orcid.org/0000-0002-9376-3984
https://orcid.org/0000-0002-9515-8892
https://orcid.org/0000-0002-1446-7256

Similar Items