Targeting small molecule drugs to T cells with antibody-directed cell-penetrating gold nanoparticles

Targeting small molecule drugs to T cells with antibody-directed cell-penetrating gold nanoparticles

We sought to develop a nanoparticle vehicle that could efficiently deliver small molecule drugs to target lymphocyte populations. The synthesized amphiphilic organic ligand-protected gold nanoparticles (amph-NPs) were capable of sequestering large payloads of small molecule drugs within hydrophobic...

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Bibliographic Details
Main Authors: Bekdemir, Ahmet, Watson, Nicki, Ingram, Jessica, Stellacci, Francesco R., Yang, Yu-Sang Sabrina, Moynihan, Kelly Dare, Dichwalkar, Tanmay M, Noh, Michelle M., Melo, Mariane Bandeira, Suh, Heikyung, Ploegh, Hidde, Irvine, Darrell J
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Royal Society of Chemistry 2019
Online Access:http://hdl.handle.net/1721.1/120167
https://orcid.org/0000-0003-0787-298X
https://orcid.org/0000-0002-1090-6071

Internet

http://hdl.handle.net/1721.1/120167
https://orcid.org/0000-0003-0787-298X
https://orcid.org/0000-0002-1090-6071

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