Intensity normalization of two-photon microscopy images for liver fibrosis analysis

This paper presents an intensity normalization method for analysis of liver tissue images, acquired using the two-photon microscopy system at different stages of fibrosis. Image informatics methods require precise intensity segmentation for analysis of collagen, vessel and cellular structures. Inten...

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Bibliographic Details
Main Authors: Singh, Vijay Raj, Rajapakse, Jagath C., Yu, Hanry, So, Peter T. C.
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Published: SPIE 2019
Online Access:http://hdl.handle.net/1721.1/120485
https://orcid.org/0000-0002-0339-3685
https://orcid.org/0000-0003-4698-6488