Stabilized single-injection inactivated polio vaccine elicits a strong neutralizing immune response

Vaccination in the developing world is hampered by limited patient access, which prevents individuals from receiving the multiple injections necessary for protective immunity. Here, we developed an injectable microparticle formulation of the inactivated polio vaccine (IPV) that releases multiple pul...

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Bibliographic Details
Main Authors: Tzeng, Stephany Y, McHugh, Kevin J, Behrens, Adam, Rose, Sviatlana, Sugarman, James L, Ferber, Shiran, Langer, Robert S, Jaklenec, Ana
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Published: National Academy of Sciences (U.S.) 2019
Online Access:http://hdl.handle.net/1721.1/120496
https://orcid.org/0000-0001-7340-0556
https://orcid.org/0000-0001-6801-4431
https://orcid.org/0000-0002-8366-3488
https://orcid.org/0000-0003-4255-0492