Positional specificity of different transcription factor classes within enhancers

Gene expression is controlled by sequence-specific transcription factors (TFs), which bind to regulatory sequences in DNA. TF binding occurs in nucleosome-depleted regions of DNA (NDRs), which generally encompass regions with lengths similar to those protected by nucleosomes. However, less is known...

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Bibliographic Details
Main Authors: Engreitz, Jesse, Ray, John P., Nguyen, Tung H., Hacohen, Nir, Grossman, Sharon Rachel, Lander, Eric Steven
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: National Academy of Sciences (U.S.) 2019
Online Access:http://hdl.handle.net/1721.1/120542
https://orcid.org/0000-0001-5410-7274