Inflamed neutrophils sequestered at entrapped tumor cells via chemotactic confinement promote tumor cell extravasation

Systemic inflammation occurring around the course of tumor progression and treatment are often correlated with adverse oncological outcomes. As such, it is suspected that neutrophils, the first line of defense against infection, may play important roles in linking inflammation and metastatic seeding...

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Bibliographic Details
Main Authors: Chen, Michelle B, Hajal, Cynthia, Benjamin, David Colin, Yu, Cathy Y., Azizgolshani, Hesham, Hynes, Richard O, Kamm, Roger Dale
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Proceedings of the National Academy of Sciences 2019
Online Access:http://hdl.handle.net/1721.1/120579
https://orcid.org/0000-0001-5418-5133
https://orcid.org/0000-0001-5215-6777
https://orcid.org/0000-0003-4682-9677
https://orcid.org/0000-0001-7603-8396
https://orcid.org/0000-0002-7232-304X