Inflamed neutrophils sequestered at entrapped tumor cells via chemotactic confinement promote tumor cell extravasation
Systemic inflammation occurring around the course of tumor progression and treatment are often correlated with adverse oncological outcomes. As such, it is suspected that neutrophils, the first line of defense against infection, may play important roles in linking inflammation and metastatic seeding...
Main Authors: | Chen, Michelle B, Hajal, Cynthia, Benjamin, David Colin, Yu, Cathy Y., Azizgolshani, Hesham, Hynes, Richard O, Kamm, Roger Dale |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Published: |
Proceedings of the National Academy of Sciences
2019
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Online Access: | http://hdl.handle.net/1721.1/120579 https://orcid.org/0000-0001-5418-5133 https://orcid.org/0000-0001-5215-6777 https://orcid.org/0000-0003-4682-9677 https://orcid.org/0000-0001-7603-8396 https://orcid.org/0000-0002-7232-304X |
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