Immunogenic Cell Death Amplified by Co-localized Adjuvant Delivery for Cancer Immunotherapy

Despite their potential, conventional whole-cell cancer vaccines prepared by freeze-thawing or irradiation have shown limited therapeutic efficacy in clinical trials. Recent studies have indicated that cancer cells treated with certain chemotherapeutics, such as mitoxantrone, can undergo immunogenic...

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Bibliographic Details
Main Authors: Fan, Yuchen, Kuai, Rui, Xu, Yao, Ochyl, Lukasz J., Moon, James J., Irvine, Darrell J
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: American Chemical Society (ACS) 2019
Online Access:http://hdl.handle.net/1721.1/120592