Helicobacter hepaticus cytolethal distending toxin promotes intestinal carcinogenesis in 129Rag2‐deficient mice
Multiple pathogenic Gram-negative bacteria produce the cytolethal distending toxin (CDT) with activity of DNase I; CDT can induce DNA double-strand breaks (DSBs), G2/M cell cycle arrest, and apoptosis in cultured mammalian cells. However, the link of CDT to in vivo tumorigenesis is not fully underst...
| Main Authors: | , , , , , |
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| 格式: | 文件 |
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Wiley
2019
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| 在线阅读: | http://hdl.handle.net/1721.1/120745 https://orcid.org/0000-0001-9307-6116 |