Genetic dissection of the miR-200–Zeb1 axis reveals its importance in tumor differentiation and invasion

The epithelial-to-mesenchymal transition (EMT) is an important mechanism for cancer progression and metastasis. Numerous in vitro and tumor-profiling studies point to the miR-200–Zeb1 axis as crucial in regulating this process, yet in vivo studies involving its regulation within a physiological cont...

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Bibliographic Details
Main Authors: Title, Alexandra C., Pires, Nuno D., Hasenöhrl, Lynn, Godbersen, Svenja, Stokar-Regenscheit, Nadine, Stoffel, Markus, Hong, Sue-Jean, Bartel, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Nature Publishing Group 2019
Online Access:http://hdl.handle.net/1721.1/120917
https://orcid.org/0000-0002-3872-2856