Genetic dissection of the miR-200–Zeb1 axis reveals its importance in tumor differentiation and invasion
The epithelial-to-mesenchymal transition (EMT) is an important mechanism for cancer progression and metastasis. Numerous in vitro and tumor-profiling studies point to the miR-200–Zeb1 axis as crucial in regulating this process, yet in vivo studies involving its regulation within a physiological cont...
Main Authors: | Title, Alexandra C., Pires, Nuno D., Hasenöhrl, Lynn, Godbersen, Svenja, Stokar-Regenscheit, Nadine, Stoffel, Markus, Hong, Sue-Jean, Bartel, David |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Published: |
Nature Publishing Group
2019
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Online Access: | http://hdl.handle.net/1721.1/120917 https://orcid.org/0000-0002-3872-2856 |
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