Microfluidic active loading of single cells enables analysis of complex clinical specimens

A fundamental trade-off between flow rate and measurement precision limits performance of many single-cell detection strategies, especially for applications that require biophysical measurements from living cells within complex and low-input samples. To address this, we introduce ‘active loading’, a...

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Bibliographic Details
Main Authors: Malinowski, Seth W., Touat, Mehdi, Ligon, Keith L., Calistri, Nicholas L, Kimmerling, Robert John, Stevens, Mark M., Olcum, Selim A., Manalis, Scott R
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Nature Publishing Group 2019
Online Access:http://hdl.handle.net/1721.1/120941
https://orcid.org/0000-0002-8541-0919
https://orcid.org/0000-0001-9939-764X
https://orcid.org/0000-0002-5702-8667
https://orcid.org/0000-0002-6417-1007
https://orcid.org/0000-0001-5223-9433