Dynamic regulation of dynein localization revealed by small molecule inhibitors of ubiquitination enzymes

Cytoplasmic dynein is a minus-end-directed microtubule-based motor that acts at diverse subcellular sites. During mitosis, dynein localizes simultaneously to the mitotic spindle, spindle poles, kinetochores and the cell cortex. However, it is unclear what controls the relative targeting of dynein to...

Full description

Bibliographic Details
Main Authors: Monda, Julie Kathryn, Cheeseman, Iain M
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Royal Society 2019
Online Access:http://hdl.handle.net/1721.1/120942
https://orcid.org/0000-0003-3851-5539
https://orcid.org/0000-0002-3829-5612