A quasi-integral controller for adaptation of genetic modules to variable ribosome demand
The behavior of genetic circuits is often poorly predictable. A gene’s expression level is not only determined by the intended regulators, but also affected by changes in ribosome availability imparted by expression of other genes. Here we design a quasi-integral biomolecular feedback controller tha...
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| Format: | Article |
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Nature Publishing Group
2019
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| Online Access: | http://hdl.handle.net/1721.1/121039 https://orcid.org/0000-0003-2435-480X https://orcid.org/0000-0002-1097-0401 https://orcid.org/0000-0001-6472-8576 |