MaGIC: a machine learning tool set and web application for monoallelic gene inference from chromatin

Background: A large fraction of human and mouse autosomal genes are subject to random monoallelic expression (MAE), an epigenetic mechanism characterized by allele-specific gene expression that varies between clonal cell lineages. MAE is highly cell-type specific and mapping it in a large number of...

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Bibliographic Details
Main Authors: Vinogradova, Svetlana, Ward, Henry N, Vigneau, Sébastien, Gimelbrant, Alexander A, Saksena, Sachit Dinesh
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:English
Published: BioMed Central 2019
Online Access:http://hdl.handle.net/1721.1/121085