High-resolution genome-wide functional dissection of transcriptional regulatory regions and nucleotides in human

Genome-wide epigenomic maps have revealed millions of putative enhancers and promoters, but experimental validation of their function and high-resolution dissection of their driver nucleotides remain limited. Here, we present HiDRA (High-resolution Dissection of Regulatory Activity), a combined expe...

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Bibliographic Details
Main Authors: Goggin, Sarah M., Saadat, Alham, Wang, Li, Sinnott-Armstrong, Nasa, Wang, Xinchen, He, Liang, Kellis, Manolis, Claussnitzer, Melina
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Published: Nature Publishing Group 2019
Online Access:http://hdl.handle.net/1721.1/121106
https://orcid.org/0000-0003-2450-736X