Dynamic control of endogenous metabolism with combinatorial logic circuits

Controlling gene expression during a bioprocess enables real-time metabolic control, coordinated cellular responses, and staging order-of-operations. Achieving this with small molecule inducers is impractical at scale and dynamic circuits are difficult to design. Here, we show that the same set of s...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Moser, Felix, Espah Borujeni, Amin, Ghodasara, Amar Navin, Cameron, Douglas, Park, YongJin, Voigt, Christopher A.
מחברים אחרים: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
פורמט: Article
יצא לאור: Nature Publishing Group 2019
גישה מקוונת:http://hdl.handle.net/1721.1/121120
https://orcid.org/0000-0002-7762-3084
https://orcid.org/0000-0002-3036-7183
https://orcid.org/0000-0001-5409-1831
https://orcid.org/0000-0002-6788-2429
https://orcid.org/0000-0003-0844-4776

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