Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age
Long-term hematopoietic stem cells (LT-HSCs) maintain hematopoietic output throughout an animal's lifespan. However, with age, the balance is disrupted, and LT-HSCs produce a myeloid-biased output, resulting in poor immune responses to infectious challenge and the development of myeloid leukemi...
| Príomhchruthaitheoirí: | , , , , , , , , , , |
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| Formáid: | Alt |
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Elsevier
2019
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| Rochtain ar líne: | https://hdl.handle.net/1721.1/121253 |