Transnuclear CD8 T cells specific for the immunodominant epitope Gra6 lower acute-phase Toxoplasma gondii burden

Transnuclear CD8 T cells specific for the immunodominant epitope Gra6 lower acute-phase Toxoplasma gondii burden

We generated a CD8 T-cell receptor (TCR) transnuclear (TN) mouse specific to the Ld-restricted immunodominant epitope of GRA6 from Toxoplasma gondii as a source of cells to facilitate further investigation into the CD8 T-cell-mediated response against this pathogen. The TN T cells bound Ld-Gra6 tetr...

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Bibliographic Details
Main Authors: Sanecka, Anna, Yoshida, Nagisa, Dougan, Stephanie K., Jackson, John, Shastri, Nilabh, Ploegh, Hidde, Blanchard, Nicolas, Frickel, Eva-Maria
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Wiley 2019
Online Access:https://hdl.handle.net/1721.1/121329

Internet

https://hdl.handle.net/1721.1/121329

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