Dynamic redox balance directs the oocyte-to-embryo transition via developmentally controlled reactive cysteine changes

The metabolic and redox state changes during the transition from an arrested oocyte to a totipotent embryo remain uncharacterized. Here, we applied state-of-the-art, integrated methodologies to dissect these changes in Drosophila. We demonstrate that early embryos have a more oxidized state than mat...

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Bibliographic Details
Main Authors: Petrova, Boryana, Liu, Keke, Tian, Caiping, Kitaoka, Maiko, Freinkman, Elizaveta, Yang, Jing, Orr-Weaver, Terry
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: National Academy of Sciences (U.S.) 2019
Online Access:https://hdl.handle.net/1721.1/121332