Dynamic redox balance directs the oocyte-to-embryo transition via developmentally controlled reactive cysteine changes
The metabolic and redox state changes during the transition from an arrested oocyte to a totipotent embryo remain uncharacterized. Here, we applied state-of-the-art, integrated methodologies to dissect these changes in Drosophila. We demonstrate that early embryos have a more oxidized state than mat...
Main Authors: | Petrova, Boryana, Liu, Keke, Tian, Caiping, Kitaoka, Maiko, Freinkman, Elizaveta, Yang, Jing, Orr-Weaver, Terry |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Published: |
National Academy of Sciences (U.S.)
2019
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Online Access: | https://hdl.handle.net/1721.1/121332 |
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