Stochasticity is necessary for multiple attractors in a class of differentiation networks
Deterministic models remain the most common option for modeling gene regulatory networks even when the underlying assumptions of high copy numbers and fast promoter kinetics are unsatisfied. Here, we analyze a widely studied differentiation network motif known as the PU.1-GATA-1 circuit and we show...
Main Authors: | Kumar, Nithin Senthur, Al-Radhawi, Muhammad Ali, Sontag, Eduardo D., Del Vecchio, Domitilla |
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Other Authors: | Massachusetts Institute of Technology. Department of Mechanical Engineering |
Format: | Article |
Language: | en_US |
Published: |
Institute of Electrical and Electronics Engineers (IEEE)
2019
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Online Access: | https://hdl.handle.net/1721.1/121528 |
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