Ultrasound-Mediated Delivery of RNA to Colonic Mucosa of Live Mice

Ultrasound-Mediated Delivery of RNA to Colonic Mucosa of Live Mice

Background & Aims It is a challenge to deliver nucleic acids to gastrointestinal (GI) tissues due to their size and need for intracellular delivery. They are also extremely susceptible to degradation by nucleases, which are ubiquitous in the GI tract. We investigated whether ultrasound, which ca...

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Bibliographic Details
Main Authors: Schoellhammer, Carl Magnus, Lauwers, Gregory Y., Goettel, Jeremy A., Oberli, Matthias, Cleveland, Cody, Park, June Y., Minahan Jr, Daniel J, Chen, Yiyun, Anderson, Daniel Griffith, Jaklenec, Ana, Snapper, Scott B., Langer, Robert S, Traverso, Giovanni
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: Elsevier BV 2019
Online Access:https://hdl.handle.net/1721.1/121977

Internet

https://hdl.handle.net/1721.1/121977

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