Identification of cell cycle-targeting microRNAs through genome-wide screens

Identification of cell cycle-targeting microRNAs through genome-wide screens

By performing nine genome-wide microRNA (miRNA) screens, we recently uncovered a new class of miRNAs, which target multiple cyclins and cyclin-dependent kinases (CDKs). Systemic delivery of selected cell cycle-targeting miRNAs to mouse xenograft models resulted in potent anti-tumorigenic effects wit...

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Bibliographic Details
Main Authors: Bogorad, Roman, Yin, Hao, Anderson, Daniel Griffith
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:English
Published: Informa UK Limited 2019
Subjects:
Developmental Biology
Cell Biology
Molecular Biology
Online Access:https://hdl.handle.net/1721.1/121999

Internet

https://hdl.handle.net/1721.1/121999

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