Identification of cell cycle-targeting microRNAs through genome-wide screens
By performing nine genome-wide microRNA (miRNA) screens, we recently uncovered a new class of miRNAs, which target multiple cyclins and cyclin-dependent kinases (CDKs). Systemic delivery of selected cell cycle-targeting miRNAs to mouse xenograft models resulted in potent anti-tumorigenic effects wit...
Main Authors: | Bogorad, Roman, Yin, Hao, Anderson, Daniel Griffith |
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Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | English |
Published: |
Informa UK Limited
2019
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Subjects: | |
Online Access: | https://hdl.handle.net/1721.1/121999 |
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