Silencing the CSF-1 Axis Using Nanoparticle Encapsulated siRNA Mitigates Viral and Autoimmune Myocarditis

Silencing the CSF-1 Axis Using Nanoparticle Encapsulated siRNA Mitigates Viral and Autoimmune Myocarditis

Myocarditis is an inflammatory disease of the heart muscle most commonly caused by viral infection and often maintained by autoimmunity. Virus-induced tissue damage triggers chemokine production and, subsequently, immune cell infiltration with pro-inflammatory and pro-fibrotic cytokine production fo...

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Bibliographic Details
Main Authors: Meyer, Ingmar Sören, Goetzke, Carl Christoph, Kespohl, Meike, Sauter, Martina, Heuser, Arnd, Eckstein, Volker, Vornlocher, Hans-Peter, Anderson, Daniel Griffith, Haas, Jan, Meder, Benjamin, Katus, Hugo Albert, Klingel, Karin, Beling, Antje, Leuschner, Florian
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:English
Published: Frontiers Media SA 2019
Online Access:https://hdl.handle.net/1721.1/122038

Internet

https://hdl.handle.net/1721.1/122038

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