Copper Hydride Catalyzed Enantioselective Synthesis of Axially Chiral 1,3-Disubstituted Allenes
The general enantioselective synthesis of axially chiral disubstituted allenes from prochiral starting materials remains a long-standing challenge in organic synthesis. Here, we report an efficient enantio- and chemoselective copper hydride catalyzed semireduction of conjugated enynes to furnish 1,3...
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Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS)
2019
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Online Access: | https://hdl.handle.net/1721.1/122287 |