Total Synthesis and Anti-Cancer Activity of All Known Communesin Alkaloids and Related Derivatives
A unified enantioselective total synthesis and anticancer evaluation of all known epoxide-containing communesin alkaloids and related derivatives is described. Our synthesis is predicated on the convergent and modular diazene-directed assembly of two complex fragments to secure the critical C3a-C3a&...
Main Authors: | Pompeo, Matthew M, Cheah, Jaime H, Movassaghi, Mohammad |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS)
2019
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Online Access: | https://hdl.handle.net/1721.1/122288 |
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