Statistical Binning for Barcoded Reads Improves Downstream Analyses

Sequencing technologies are capturing longer-range genomic information at lower error rates, enabling alignment to genomic regions that are inaccessible with short reads. However, many methods are unable to align reads to much of the genome, recognized as important in disease, and thus report errone...

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Bibliographic Details
Main Authors: Shajii, Ariya, Numanagic, Ibrahim, Whelan, Christopher, Berger Leighton, Bonnie
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:English
Published: Elsevier BV 2019
Online Access:https://hdl.handle.net/1721.1/122938