Joker de Bruijn: Covering k-Mers Using Joker Characters

Sequence libraries that cover all k-mers enable universal and unbiased measurements of nucleotide and peptide binding. The shortest sequence to cover all k-mers is a de Bruijn sequence of length. Researchers would like to increase k to measure interactions at greater detail, but face a challenging p...

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Bibliographic Details
Main Authors: Orenstein, Yaron, Yu, Yun William, Berger Leighton, Bonnie
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:English
Published: Mary Ann Liebert Inc 2019
Online Access:https://hdl.handle.net/1721.1/122940