Unraveling the Paradox of Statins with Human Neurons: New Leads in Alzheimer’s Disease

Conflicting clinical studies have reported that statins both reduce and accelerate cognitive impairments in Alzheimer’s disease. In this issue, Van der Kant et al. (2019) use iPSC-derived neurons to thoroughly dissect the link between cholesterol synthesis, phospho-Tau, and amyloid-β, revealing new...

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Bibliographic Details
Main Authors: Blanchard, Joel W., Tsai, Li-Huei
Other Authors: Picower Institute for Learning and Memory
Format: Article
Published: Elsevier BV 2019
Online Access:https://hdl.handle.net/1721.1/122952