Unraveling the Paradox of Statins with Human Neurons: New Leads in Alzheimer’s Disease
Conflicting clinical studies have reported that statins both reduce and accelerate cognitive impairments in Alzheimer’s disease. In this issue, Van der Kant et al. (2019) use iPSC-derived neurons to thoroughly dissect the link between cholesterol synthesis, phospho-Tau, and amyloid-β, revealing new...
Main Authors: | Blanchard, Joel W., Tsai, Li-Huei |
---|---|
Other Authors: | Picower Institute for Learning and Memory |
Format: | Article |
Published: |
Elsevier BV
2019
|
Online Access: | https://hdl.handle.net/1721.1/122952 |
Similar Items
-
Cholesterol, statins, and Alzheimer disease.
by: Alexei R Koudinov, et al.
Published: (2005-03-01) -
Cholesterol, Statins, and Alzheimer Disease
by: Berezov Temirbolat T
Published: (2005-01-01) -
Editorial: Understanding human biology with iPSC derived cell types in the Era of CRISPR technology
by: Huinan Li, et al.
Published: (2023-12-01) -
Protective Effects of Statins against Alzheimer Disease
by: Leila Rezakhani, et al.
Published: (2023-10-01) -
Transthyretin and the brain re-visited: Is neuronal synthesis of transthyretin protective in Alzheimer's disease?
by: Li Xinyi, et al.
Published: (2011-11-01)