A Developmental Switch in Microglial HDAC Function

The epigenetic mechanisms controlling microglia functions are largely unknown. In this issue of Immunity, Datta et al. (2018) uncover surprising and distinct effects of deleting the epigenetic regulators HDAC1 and HDAC2 during microglial development versus during the course of neurodegeneration.

Bibliographic Details
Main Authors: Mathys, Hansruedi, Penney, Jay, Tsai, Li-Huei
Other Authors: Picower Institute for Learning and Memory
Format: Article
Published: Elsevier BV 2019
Online Access:https://hdl.handle.net/1721.1/122954